Back to Our ScienceBig Data Analytics Courtesy of Pacific Biosciences of California, Inc., Menlo Park, CA, USAAn unbiased, data-driven approach to CAR developmentWe leverage big data analytics and our global infrastructure to discover and develop CAR-T therapies that are rooted in science and benchmarked against best-in-class molecules. We screen our innovative, in-house libraries for the best CAR constructs for a given indication, guided by automated analysis of big datasets. This provides us the candidate diversity to take data-driven risks permitting multiple “shots on goal”. Monitoring Darwinian evolution through molecular genetics to find the best CARsOur infrastructure, data transfer platform, and analytics capabilities allow us to cast a wider net to find the best CAR attributes. Our approach has three key advantages: Providing sufficient library diversity in the final product configuration Using biologically relevant cell types, e.g. primary human cells, instead of immortalized cell line models Applying physiologically relevant screens instead of artificial environments When applied through our big data analytics platform, this allows us to find rare events with significantly improved attributes. Our Data Never SleepsOur global presence allows for round-the-clock building, testing, and analysis; DNA constructs are developed in George Town, assembled in Shanghai, and analyzed in West Palm Beach for further refinement and optimization.