Director, Research and Development Oncology / CAR-T
Location: Shanghai, China
Exuma Biotech Corp and Shanghai Exuma Biotechnology Co., are looking for another individual to share our passion for making a lasting difference in the fight against cancer.
Position: Director, Research and Development Oncology/CAR-T
Location: Shanghai, China
The big picture is:
EXUMA leverages its globally integrated science, development and informatics teams located across multiple time zones to accelerate the design, high-throughput screening, discovery and development of chimeric antigen receptor T cell (CAR-T) candidates for both solid and liquid tumor malignancies. The company is developing logic gated CAR-T platforms to advance TME-restricted cellular therapies for solid tumors, platforms that will allow for same day, rapid point of care (rPOC) administration for solid or liquid tumors, and highly scalable systems for global therapy deployment, beginning in Asia.
Why Join Us?
EXUMA is a clinical-stage biotechnology company committed to discovering, developing and commercializing CAR-T therapies for the treatment of cancer. Founded in 2015, the company has rapidly built its core technologies with a growing global presence with operations in China (Shanghai and Shenzhen), Grand Cayman, and in West Palm Beach, Florida.
This is a full-time position with Shanghai Exuma Biotechnology located at:
Room 301~305, Building 1, Guangang Industrial Park, No. 2715 Longwu Road, Xuhui District, Shanghai
Here are some of the responsibilities:
1，Responsible for the establishment of the company’s CAR-T technology research and development platform, the research and development of cellular immune related technology products, and the management of the research and development team;
2，Including establishment, verification and screening of in-vitro experiment methods of the company’s products under research, design of in-vivo animal experiments, communication and management with outsourcing companies;包括公司在研发产品的体外实验方法的建立，验证和筛选，体内动物实验的设计，与外包公司沟通和管理；
3，Recruit and train personnel involved in R&D, manage and supervise the progress of the project’s R&D personnel, arrange experiments reasonably, complete the project within the prescribed time, and be responsible for the setting and implementation of the annual work plan and work goals of the R&D department, and evaluation;参与研发的人员招聘和培训，管理并监督项目研发人员的工作进展，合理安排实验，在规定的时间内完成项目，负责研发部门年度工作计划和工作目标的设定与实施，以及评估；
4，Participate in CAR-T related patent declaration, participate in IND declaration related work, and can cooperate with CMC, QA, QC and Regulatory and other departments;
5，Ability to flexibly accept other related work arrangements.
We are looking for candidates with this background and education:
1，PhD degree in immunology, cell biology, molecular biology and other related majors, with a good theoretical basis for immune cell therapy;免疫学、细胞生物学、分子生物学相关专业博士学历，具有较好的免疫细胞治疗理论基础；
2，More than five years of work experience in related companies, more than three years of experience in cell therapy research and development management;
3，Familiar with CRISPR gene editing technology, CAR vector construction and optimization, cell function test (FACS, cytokine release) and other technologies related to CAR-T products, and familiar with animal drug efficacy and design of pharmacokinetic experiments;
4，Possess a certain team organization management ability and team cooperation communication ability, have practical scientific research experience, understand the application and development of cell therapy technology;
5，Innovative spirit and systematic rigorous research thinking;
6，Excellent English reading and writing skills, need to use oral English to communicate and write English reports.
To apply or obtain additional information, contact:
Tel: +86 13818184277