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Director, Research and Development Oncology / CAR-T

Director, Research and Development Oncology / CAR-T

Location: Shanghai, China

 

Exuma Biotech Corp and Shanghai Exuma Biotechnology Co., are looking for another individual to share our passion for making a lasting difference in the fight against cancer.

美国埃秀马生物技术公司和上海埃秀马生物技术有限公司正在寻找可以分享我们的激情和在对抗癌症的斗争中做出持久的改变的人。

Position: Director, Research and Development Oncology/CAR-T

Location: Shanghai, China

职务:研发肿瘤/ CAR-T总监

地点:中国上海

The big picture is:

总体情况是:

EXUMA leverages its globally integrated science, development and informatics teams located across multiple time zones to accelerate the design, high-throughput screening, discovery and development of chimeric antigen receptor T cell (CAR-T) candidates for both solid and liquid tumor malignancies. The company is developing logic gated CAR-T platforms to advance TME-restricted cellular therapies for solid tumors, platforms that will allow for same day, rapid point of care (rPOC) administration for solid or liquid tumors, and highly scalable systems for global therapy deployment, beginning in Asia.

Exuma利用其跨多个时区的全球综合科学、开发和信息学团队,加速设计、高通量筛选、发现和开发适用于实体和液体肿瘤、恶性肿瘤的嵌合抗原受体T细胞(CAR-T)。公司正在开发CAR-T平台,以推进实体瘤的TME限制性细胞治疗、允许当天使用的平台、固体或液体肿瘤的快速护理点(rPOC)管理,以及从亚洲开始的全球治疗部署的高度可扩展系统。

 

Why Join Us?

为什么加入我们?

EXUMA is a clinical-stage biotechnology company committed to discovering, developing and commercializing CAR-T therapies for the treatment of cancer. Founded in 2015, the company has rapidly built its core technologies with a growing global presence with operations in China (Shanghai and Shenzhen), Grand Cayman, and in West Palm Beach, Florida.

This is a full-time position with Shanghai Exuma Biotechnology located at:

上海市徐汇区龙吴路2715号关港工业园区1栋301~305室

Room 301~305, Building 1, Guangang Industrial Park, No. 2715 Longwu Road, Xuhui District, Shanghai

 

Here are some of the responsibilities:

以下是一些职责:

1,Responsible for the establishment of the company’s CAR-T technology research and development platform, the research and development of cellular immune related technology products, and the management of the research and development team;

负责公司CAR-T技术研发平台的建立,细胞免疫相关技术产品的研发,以及研发团队的管理;

2,Including establishment, verification and screening of in-vitro experiment methods of the company’s products under research, design of in-vivo animal experiments, communication and management with outsourcing companies;包括公司在研发产品的体外实验方法的建立,验证和筛选,体内动物实验的设计,与外包公司沟通和管理;

3,Recruit and train personnel involved in R&D, manage and supervise the progress of the project’s R&D personnel, arrange experiments reasonably, complete the project within the prescribed time, and be responsible for the setting and implementation of the annual work plan and work goals of the R&D department, and evaluation;参与研发的人员招聘和培训,管理并监督项目研发人员的工作进展,合理安排实验,在规定的时间内完成项目,负责研发部门年度工作计划和工作目标的设定与实施,以及评估;

4,Participate in CAR-T related patent declaration, participate in IND declaration related work, and can cooperate with CMC, QA, QC and Regulatory and other departments;

参与CAR-T相关专利的申报,参与IND申报相关工作,能够与CMC,QA,QC和Regulatory等各部门协同工作;

5,Ability to flexibly accept other related work arrangements.

能够灵活接受其他相关的工作安排。

 

We are looking for candidates with this background and education:

我们正在寻找具有这种背景和教育背景的候选人:

1,PhD degree in immunology, cell biology, molecular biology and other related majors, with a good theoretical basis for immune cell therapy;免疫学、细胞生物学、分子生物学相关专业博士学历,具有较好的免疫细胞治疗理论基础;

2,More than five years of work experience in related companies, more than three years of experience in cell therapy research and development management;

五年以上相关企业工作经验,三年以上细胞治疗研发管理经验;

3,Familiar with CRISPR gene editing technology, CAR vector construction and optimization, cell function test (FACS, cytokine release) and other technologies related to CAR-T products, and familiar with animal drug efficacy and design of pharmacokinetic experiments;

熟悉CRISPR基因编辑技术、CAR载体构建与优化,细胞功能试验(FACS,细胞因子释放)等与CAR-T产品相关的技术,熟悉动物药效和药代实验的设计;

4,Possess a certain team organization management ability and team cooperation communication ability, have practical scientific research experience, understand the application and development of cell therapy technology;

具备一定的团队组织管理能力和团队合作沟通能力,拥有实际科研经验,了解细胞治疗技术的应用和发展;

5,Innovative spirit and systematic rigorous research thinking;

有创新精神,具备系统严谨的研究思维;

6,Excellent English reading and writing skills, need to use oral English to communicate and write English reports.

优秀的英语读写说功底,需流利地用英语口语交流并撰写英文报告。

 

To apply or obtain additional information, contact:

要应用或获取其他信息,请联系:

Email: jjtao@exumabio.com

Tel:   +86 13818184277